Welcome to the Ishihara lab! Novel immunotherapy development in London
We are a Drug Design Lab, creating safe and efficacious drugs based on strong science.
We are working to address the challenges of difficult-to-treat diseases through translational immunology.
The Ishihara lab's capability: Lab introduction.pdf
The news on our immunotherapy development activity for brain cancer
Ishihara's interview
Research
Developing new classes of immunotherapy to solve autoimmune diseases
We take unique approaches to I&I (inflammation and immunology) research. Current immunotherapies remove excess pro-inflammatory molecules or deplete malignant immune cells. Instead, we seek to induce anti-inflammatory immune cell phenotypes using the body's natural response. Our approach can be useful for various autoimmune and inflammatory diseases, including type 1 diabetes, rheumatoid arthritis, IBD, multiple sclerosis, and infectious diseases.
Making cancer therapy safe and effective
We are keen to develop new cancer medicines with bioengineering methods. Cancer immunotherapy is a very promising approach used in the clinic. However, current therapies are not effective for every patient and are prone to toxicities. We are developing technologies that can deliver cancer drugs specifically to the tumour. Our targeted immunotherapy will improve the safety and efficacy of current treatments. Our goal is to translate our technologies to the clinic. We improve immune checkpoint inhibitors, cytokine therapies, CAR-T cells and TCR-T cells. We have ongoing pharma companies collaboration and clinical translational activities. Ishihara founded a company called ArrowImmune Inc.
Development of new protein vaccine
Using our platform technology to deliver antigen to a specific organ and cells, we are now investigating a new idea of efficient antigen recognition for vaccine development.